Our department has expertise in assessing the biochemical mechanisms that underpin immunological and inflammatory responses in the eye (e.g. corneal and retinal) and on the eye's surface (e.g. in conditions of dry eye and contact lens wear), both in humans and in animal models of disease and injury.
Research methods include in vivo and ex vivo analysis of corneal and retinal inflammation (e.g. confocal, epifluorescent and light microscopy), analysis of chemokine and cytokine gene expression and production (qPCR and ELISA), and generation of bone marrow chimeras to study the contribution of resident versus infiltrating monocyte-derived cells.
Research groups working within this theme include: