Optological Laboratory

Research Overview

The Optological Laboratory non-invasively investigates how the human eye and brain function, both in normal observers and those with eye disease. Although our understanding of neuroscience has been greatly enhanced through electrophysiological recordings from individual neurons and through computer imaging of gross neural activity across the brain, such information only tells us part of how the brain and eye work. Ultimately we also need to understand how the eye and brain behave in response to various forms of information, and to ascertain what functional limits exist in processing such information. Only by combining results from a range of different studies – including electrophysiological, imaging and behavioural studies – can a more complete understanding of neuroscience be achieved.

Our laboratory uses a range of techniques to determine how the eye and brain behave, many of which can be classed under the general heading of psychophysical methods. Sometimes our investigations involve visual targets used in clinical tests of vision, allowing us to better understand how such tests work and allowing more effective clinical tests to be developed. Other investigations use customised visual stimuli and special experimental protocols to examine how the eye transmits information to the brain, and also how the brain processes this information in order to make decisions. The laboratory is well equipped to undertake a wide range of behavioural experiments and so can address a broad range of behavioural questions, both in the clinical and basic sciences.

Staff

  • Dr Frank Giorlando (PhD candidate)
  • Ms Adela Park (PhD candidate)
  • Mr Mohammadreza Moniritilaki (MSc candidate)

Collaborators

  • Professor RHS Carpenter - Gonville and Caius College, University of Cambridge, Cambridge, UK
  • Dr Ruth Hogg - Centre for Vision & Vascular Science, Institute of Clinical Sciences, Royal Victoria Hospital, Belfast
  • Dr Chris A Johnson - Department of Ophthalmology, University of Iowa, USA
  • Assoc Prof Nikolaos Smyrnis, National and Kapodistrian University of Athens, Greece
  • Dr Matthew Stainer - School of Psychology, University of Aberdeen, UK

Funding

ARC