Understanding progressive vision loss in the eye disease glaucoma

Project Details

Glaucoma is the second leading cause of irreversible vision loss in elderly Australians, and is a major cause of blindness worldwide. Currently the tools for determining progression of the disease are remarkably crude, however, making it difficult to determine those patients in whom standard treatments are not adequately controlling the disease. This study will produce a radically more sophisticated tool for determining progression. We will also explore how vision in lost in glaucoma at the spatial scale of a single neuron by employing advanced technologies such as adaptive optics, allowing us to determine whether there are measurable changes prior to irreversible vision loss that may be the targets of future glaucoma treatments.