A clinical test of dark adaptation for age-related macular degeneration
Age-related macular degeneration (AMD) is a common progressive disease that is becoming increasingly significant in our ageing population. Given recent developments in the treatment of the disease, there is a need for a functional test that can detect AMD early, that can monitor progression, and that can monitor treatment efficacy in clinical trials. There is evidence that cone dark adaptation is affected early in AMD, together with the normally rapid recovery of cones during dark adaptation, makes the measurement of cone dark adaptation a viable option in the time-constrained clinical setting. This project will aim to develop and verify such a test.
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