Ocular Physiology Laboratory

Research Overview

Our laboratory is interested in electrophysiology, imaging and developing novel methods for analysis and its application to understanding the risk factors for neurodegenerative diseases such as glaucoma.

Current projects include:

  • Assessing vascular autoregulation in ageing and glaucoma
  • Developing novel reversible models of glaucoma
  • Understanding the role of blood pressure in the development of glaucoma
  • Investigating the role of intracranial pressure in glaucoma
  • Testing novel neuroprotective treatments for glaucoma
  • Evaluation of vascular, glial and functional deficits in diabetic eye disease
  • Understanding the reasons for progressive vision loss in retinopathy of prematurity
  • Testing novel treatments for abnormal blood vessel growth
  • Wireless visual electrophysiology and ocular imaging platform for CNS drug testing

Staff

  • Dr Zheng He

Collaborators

  • Prof John Morrison, Department of Ophthalmology, Oregon Health Sciences University, Portland Oregon, US
  • Drs Brad Fortune and Lin Wang, Devers Eye Institute, Portland Oregon, US
  • Prof Tien Y Wong, Singapore National Eye Centre, SN
  • Dr Rebecca Fish, Dr Rachel Gurrell, Neusentis, Pfizer Research & Development, Cambridge, UK
  • Dr Gvido Cebers, AstraZeneca Neuroscience, Cambridge, MA USA
  • Dr Monica Acosta, Department of Optometry & Vision Sciences, University of Auckland, NZ
  • Drs Nivedita Chatterjee and Bharathi Subramaniam, Vision Research Foundation, Sankara Nethralaya, Chennai, India
  • Prof Chi-Ho To, Dr Henry Chan and Dr Dennis Tse, School of Optometry, Hong Kong PolyTechnic University, HK